Methadone
- Opioid analgesic
- Strong opioid agonist
- Activates opioid receptors
- Inhibits pain transmission
- Suppresses opioid w/drawl Sx w/ euphoria or dependence
- Moderate-severe pain
- Prevention of opioid abuse
- Orally, once per day
- Respiratory depression
- Constipation
- Confusion
- Sedation
- AVOID MAOI