Sumatriptan

-Mohamed Waheed -
0
Sumatriptan


  •  Antimigraine
  •  5-HT 1B/1D receptor agonist
  •  Activates 5-HT 1B/1D receptors

  •  Pial & dural vessel constriction Presynaptic inhibition of trigeminal peptide neurotransmitter release Inhibitions brainstem activation of trigeminal neurons

  •  Vascular HA Migraine & cluster

  •  Oral, nasal, & subQ 

  •  Dizziness

  •  Vertigo

  •  Tingling

  •  Warm sensation

  •  Tight feeling head & chest

  •  Coronary vasospasm

  •  AVOID
  1.  MAOI
  2.   SSRI

التسميات :

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